Factors influencing recurrence rates and radiological outcomes after two-stage exchange arthroplasty for prosthetic joint infection utilizing a premade antibiotic loaded cement hemiarthroplasty

Patients undergoing two-stage revision for PJI with a prefabricated antibiotic cement spacer demonstrate a high rate of recurrence (38.2%), using our conservative definition of recurrence and often become reinfected with a new bacterial species (85.7%). Patient factors are also important to consider given that recurrently infected patients were younger and had longer follow-up. A standardized definition of recurrent PJI is mandatory to accurately compare studies utilizing various treatment options.