SOX2 Expression and Regulation in Pulmonary Aplasia/Agenesis

The expression of SOX2 and BMP4 is strongly altered in pulmonary agenesis/aplasia. Thus, these proteins appear to regulate tissue-specific proliferative activity during early lung development.

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Publication Details

Journal
Pediatric and Developmental Pathology
Published
2025-06-17
DOI
https://doi.org/10.1177/10935266251349491
Primary Topic
Congenital Diaphragmatic Hernia Studies
Type
article
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article

SOX2 Expression and Regulation in Pulmonary Aplasia/Agenesis

Madeleine Joubert, Christophe Némos, Hervé Sartelet, Pauline Brice et al.
Pediatric and Developmental Pathology
Congenital Diaphragmatic Hernia Studies
article

SOX2 Expression and Regulation in Pulmonary Aplasia/Agenesis

Madeleine Joubert, Christophe Némos, Hervé Sartelet, Pauline Brice, Piolat Christian, Apostolou Alexia, Arbez Gindre Francine
article en

Abstract

The expression of SOX2 and BMP4 is strongly altered in pulmonary agenesis/aplasia. Thus, these proteins appear to regulate tissue-specific proliferative activity during early lung development.

Pediatric and Developmental PathologyVol. 28(5)
Inserm (FR), Université Joseph Fourier (FR), Centre Hospitalier Universitaire de Grenoble (FR), Centre Hospitalier Universitaire de Nantes (FR), Centre Hospitalier Universitaire de Besançon (FR), Hôpital Couple Enfant (FR), Université Grenoble Alpes (FR)
Good health and well-being
Openalex Percentile: Top 76%
Congenital Diaphragmatic Hernia Studies
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SOX2 Expression and Regulation in Pulmonary Aplasia/Agenesis — Madeleine Joubert, Christophe Némos, et al. · Pediatric and Developmental Pathology (2025) | TGRS Research Map | TGRS