Subtype-specific atypical B cell profiles in myasthenia gravis reveal distinct immunopathological pathways
MG subtypes exhibit distinct atBC profiles linked to immunopathology and disease onset. These findings reveal subtype-specific pathways that regulate atBCs and highlight their potential as therapeutic targets in both IgG1-3- and IgG4-mediated autoimmunity.
Authors
- Linda L. Kusner (ORCID: https://orcid.org/0000-0002-5530-2140)
- Leslie Jacobson
- Angela Vincent (ORCID: https://orcid.org/0000-0003-2395-8695)
- Henry J. Kaminski (ORCID: https://orcid.org/0000-0002-8195-0141)
- Patricia Sikorski (ORCID: https://orcid.org/0000-0003-4609-1174)
- Taylor Bauman
Institutions
- George Washington University (US)
- John Radcliffe Hospital (GB)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-06-18
- DOI
- https://doi.org/10.3389/fimmu.2025.1608160
- Citations
- 2
- Primary Topic
- Myasthenia Gravis and Thymoma
- Type
- article
- Field-Weighted Citation Impact
- 2.78