Electrocardiographic changes in QTc interval and other parameters associated with osimertinib therapy
This study comprehensively investigates the electrocardiographic changes before and after osimertinib treatment in patients with EGFR-mutated NSCLC. The significant prolongation of QTc intervals underscores the need for rigorous ECG monitoring to mitigate potential cardiotoxicity.
Authors
- Yichuan Jiang (ORCID: https://orcid.org/0000-0002-4365-1466)
- Yilin Pan
- Ping Yang (ORCID: https://orcid.org/0000-0002-8588-847X)
- Beibei Du
- Yuquan He (ORCID: https://orcid.org/0000-0001-5662-2990)
- Kexin Peng (ORCID: https://orcid.org/0000-0002-9750-4998)
Institutions
- Union Hospital (HK)
- Beijing Anzhen Hospital (CN)
- Union Hospital (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-06-18
- DOI
- https://doi.org/10.3389/fonc.2025.1612758
- Citations
- 1
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- Natural Science Foundation of Jilin Province
- National Natural Science Foundation of China
- Department of Finance of Jilin Province