Octreotide combined with pantoprazole in the treatment of elderly patients with peptic ulcer complicated by upper gastrointestinal bleeding

The combination of octreotide and pantoprazole is associated with improved hemostatic efficacy in elderly patients with peptic ulcers and upper gastrointestinal bleeding. It is linked to reduced hemostasis time, optimized gastric pH, and improved coagulation function. These findings suggest its potential as a promising approach for managing UGIB in this population.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2025-06-18
DOI
https://doi.org/10.3389/fphar.2025.1623530
Primary Topic
Gastrointestinal Bleeding Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Octreotide combined with pantoprazole in the treatment of elderly patients with peptic ulcer complicated by upper gastrointestinal bleeding

Shuqin Zhang, Jing Huang, Ming Yang
Frontiers in Pharmacology
Gastrointestinal Bleeding Diagnosis and Treatment
article

Octreotide combined with pantoprazole in the treatment of elderly patients with peptic ulcer complicated by upper gastrointestinal bleeding

Shuqin Zhang, Jing Huang, Ming Yang
article en

Abstract

The combination of octreotide and pantoprazole is associated with improved hemostatic efficacy in elderly patients with peptic ulcers and upper gastrointestinal bleeding. It is linked to reduced hemostasis time, optimized gastric pH, and improved coagulation function. These findings suggest its potential as a promising approach for managing UGIB in this population.

Frontiers in PharmacologyVol. 16
Wuhan University (CN), Wuhan Puai Hospital (CN), Renmin Hospital of Wuhan University (CN), Second People’s Hospital of Yibin (CN)
Good health and well-being
Openalex Percentile: Top 79%
Gastrointestinal Bleeding Diagnosis and Treatment
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