Comparative microbiome analysis of paired mucosal and fecal samples in Korean colorectal cancer patients
This study highlights distinct microbial and functional signatures in CRC, particularly from mucosal samples, which offer deeper insights into tumor-microbiota interactions. The identified microbial markers and enriched pathways may contribute to immune modulation and tumor progression. These findings support the potential for microbiome-based diagnostic and therapeutic strategies tailored to Korean CRC patients and underscore the importance of dual-sample analysis in microbiome research.
Authors
- Younggwang Kim (ORCID: https://orcid.org/0000-0002-8033-4232)
- Sanghun Lee (ORCID: https://orcid.org/0000-0002-0573-9555)
- Min Ki Kim
Institutions
- Harvard University (US)
- Hallym University (KR)
- Cancer Research And Biostatistics (US)
- Myongji Hospital (KR)
- Dankook University (KR)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-06-18
- DOI
- https://doi.org/10.3389/fonc.2025.1578861
- Citations
- 2
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- Korea Health Industry Development Institute