Qishen Yiqi alleviates periostin-mediated cardiac fibrosis and hypertrophy in Dahl hypertensive rat hearts and angiotensin II-induced cardiac organoids
QSYQ alleviates cardiac fibrosis and hypertrophy in Dahl Salt-sensitive hypertension rats <i>in vivo</i> and angiotensin II-induced cardiac organoids <i>in vitro</i> via regulating multiple signaling pathway activator periostin.
Authors
- Siwen Fan
- Guangxu Xiao (ORCID: https://orcid.org/0000-0003-3996-6622)
- Yan Zhu (ORCID: https://orcid.org/0000-0002-3197-7936)
- Siyu Li (ORCID: https://orcid.org/0000-0002-2203-9294)
- Yuhan Zhao (ORCID: https://orcid.org/0000-0002-1427-4139)
- Hongxia Du (ORCID: https://orcid.org/0000-0003-3190-7601)
- Shuang He
- Guanwei Fan
Institutions
- Tianjin University of Traditional Chinese Medicine (CN)
- First Teaching Hospital of Tianjin University of Traditional Chinese Medicine (CN)
- Tianjin haihe hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-06-18
- DOI
- https://doi.org/10.3389/fphar.2025.1491582
- Citations
- 2
- Primary Topic
- Cardiac Fibrosis and Remodeling
- Type
- article
- Field-Weighted Citation Impact
- 2.78
Funders
- National Natural Science Foundation of China
- Tianjin University