Dietary carbohydrate intake and risks of overall and 21 site-specific cancers: a prospective cohort study
Increased consumption of dietary fiber and non-free sugars is associated with a reduced risk of certain cancers (e.g., overall cancer, esophageal, colorectal, lung, and kidney cancers), potentially due to their anti-inflammatory effects, short-chain fatty acid production, and other protective mechanisms. In contrast, higher intakes of free sugars and sucrose are associated with an elevated risk (e.g., lung, kidney cancer, and non-Hodgkin lymphoma), which may be attributed to inflammation and oxidative stress.
Authors
- Yingying Mao (ORCID: https://orcid.org/0000-0003-3644-9160)
- Xiaohui Sun (ORCID: https://orcid.org/0000-0003-0823-0313)
- DU Ling-bin (ORCID: https://orcid.org/0000-0002-1992-7784)
- Bin Liu (ORCID: https://orcid.org/0000-0003-4191-8128)
- Le Wang (ORCID: https://orcid.org/0000-0002-4354-3369)
- Jiayu Li (ORCID: https://orcid.org/0000-0002-3326-1683)
- Qi Yuan
- Ding Ye (ORCID: https://orcid.org/0000-0001-6654-7832)
- Shuhui Chen (ORCID: https://orcid.org/0000-0001-7255-0026)
- Yudan Yang (ORCID: https://orcid.org/0000-0003-1561-3283)
- Baojie Hua
Institutions
- Zhejiang Chinese Medical University (CN)
- Chinese Academy of Sciences (CN)
- Zhejiang Cancer Hospital (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-06-18
- DOI
- https://doi.org/10.3389/fnut.2025.1607358
- Citations
- 3
- Primary Topic
- Nutritional Studies and Diet
- Type
- article
- Field-Weighted Citation Impact
- 5.64
Funders
- Zhejiang Chinese Medical University
- Natural Science Foundation of Zhejiang Province