NOVA1 Activation Modulates the Tumor Immune Microenvironment Through STING Phosphorylation in Head and Neck Squamous Cell Carcinoma
NOVA1 modulates the cGAS-STING pathway through STING phosphorylation and associated immune responses in HNSCC, providing potential therapeutic target for enhancing anti-tumor immunity.
Authors
- Jeehyun Helen Bae
- Sun Och Yoon (ORCID: https://orcid.org/0000-0002-5115-1402)
- Sehui Kim (ORCID: https://orcid.org/0000-0002-6640-3051)
- Hyang Mi Kim
Institutions
- Yonsei University (KR)
- Severance Hospital (KR)
- Korea University Medical Center (KR)
Publication Details
- Journal
- Cancer Research and Treatment
- Published
- 2025-06-18
- DOI
- https://doi.org/10.4143/crt.2025.333
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea