RECURRENT SPONTANEOUS SUBDURAL HEMATOMA IN A PATIENT WITH SEVERE HEMOPHILIA A: A CASE REPORT AND CLINICAL REFLECTIONS FROM A RESOURCE-LIMITED SETTING

Background: Intracranial hemorrhage (ICH) is one of the gravest complications in hemophilia, often leading to significant neurological morbidity and mortality. Spontaneous subdural hematomas (SDHs) are especially rare and pose diagnostic and therapeutic dilemmas in patients with severe coagulation defects. Case Presentation: We report a 31-year-old male with genetically confirmed severe Hemophilia A who developed recurrent spontaneous SDHs without antecedent trauma. The patient was managed conservatively with recombinant factor VIII concentrate and neurocritical care monitoring, resulting in clinical stabilization and radiological improvement. Conclusion: This case underscores the critical need for high clinical vigilance, early imaging, and aggressive factor replacement in preventing progression of hemorrhagic events in hemophilia. Structured hemophilia care networks and access to prophylactic therapy remain indispensable in resource-limited countries such as India.

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Publication Details

Journal
International Journal of Advanced Research
Published
2025-05-31
DOI
https://doi.org/10.21474/ijar01/21002
Primary Topic
Hemophilia Treatment and Research
Type
article
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article

RECURRENT SPONTANEOUS SUBDURAL HEMATOMA IN A PATIENT WITH SEVERE HEMOPHILIA A: A CASE REPORT AND CLINICAL REFLECTIONS FROM A RESOURCE-LIMITED SETTING

Athulya G Asokan
International Journal of Advanced Research
Hemophilia Treatment and Research
article

RECURRENT SPONTANEOUS SUBDURAL HEMATOMA IN A PATIENT WITH SEVERE HEMOPHILIA A: A CASE REPORT AND CLINICAL REFLECTIONS FROM A RESOURCE-LIMITED SETTING

Athulya G Asokan
article en

Abstract

Background: Intracranial hemorrhage (ICH) is one of the gravest complications in hemophilia, often leading to significant neurological morbidity and mortality. Spontaneous subdural hematomas (SDHs) are especially rare and pose diagnostic and therapeutic dilemmas in patients with severe coagulation defects. Case Presentation: We report a 31-year-old male with genetically confirmed severe Hemophilia A who developed recurrent spontaneous SDHs without antecedent trauma. The patient was managed conservatively with recombinant factor VIII concentrate and neurocritical care monitoring, resulting in clinical stabilization and radiological improvement. Conclusion: This case underscores the critical need for high clinical vigilance, early imaging, and aggressive factor replacement in preventing progression of hemorrhagic events in hemophilia. Structured hemophilia care networks and access to prophylactic therapy remain indispensable in resource-limited countries such as India.

International Journal of Advanced ResearchVol. 13(05)
Openalex Percentile: Top 82%
Hemophilia Treatment and Research
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