Oxidative stress, senescence and <scp>mRNA</scp> decay in peripheral blood mononuclear cells of women with <scp>gestational diabetes mellitus</scp> ‐link to increased <scp>cardiovascular disease</scp> risk
Markers of vascular oxidative stress and senescence are increased and correlate with indices of glucose and lipid metabolism early in pregnancy in women developing GDM. Cellular markers reflecting attenuated defence against oxidative stress and senescence decrease throughout pregnancy and at 5-year follow-up and correlate with aortic stiffness in women with previous GDM.
Authors
- Kristin Godang (ORCID: https://orcid.org/0000-0003-3407-3657)
- Thor Ueland (ORCID: https://orcid.org/0000-0001-5005-0784)
- Marie Cecilie Paasche Roland (ORCID: https://orcid.org/0000-0002-2589-9855)
- Yusuf Khan (ORCID: https://orcid.org/0000-0001-6986-4657)
- Annika E. Michelsen (ORCID: https://orcid.org/0000-0001-7207-2407)
- Tove Lekva (ORCID: https://orcid.org/0000-0002-7962-4726)
- Elisabeth Qvigstad (ORCID: https://orcid.org/0000-0002-9119-9187)
Institutions
- Oslo University Hospital (NO)
- University Hospital of North Norway (NO)
- University of Oslo (NO)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2025-06-17
- DOI
- https://doi.org/10.1111/dom.16521
- Citations
- 1
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 3.49
Funders
- Anders Jahres Fond til Vitenskapens Fremme