Estimating the effective reproduction number from wastewater (Rt): A methods comparison

While not all methods that estimate R<sub>t</sub> from wastewater produce the same results, they all provide a way to incorporate wastewater concentration data into epidemic modeling. Our results show that straightforward measures like the percent change can produce similar results of more complex models. Based on the results, researchers and public health officials can select the method that is best for their situation.

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Publication Details

Journal
Epidemics
Published
2025-06-18
DOI
https://doi.org/10.1016/j.epidem.2025.100839
Citations
6
Primary Topic
SARS-CoV-2 detection and testing
Type
article
Field-Weighted Citation Impact
8.38

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article

Estimating the effective reproduction number from wastewater (Rt): A methods comparison

David A. Larsen, Yiquan Zhou, Brittany Kmush, Dustin Hill et al.
6 citations
Epidemics
SARS-CoV-2 detection and testing
8.38
article

Estimating the effective reproduction number from wastewater (Rt): A methods comparison

David A. Larsen, Yiquan Zhou, Brittany Kmush, Dustin Hill, Mary B. Collins, E. Joe Moran, Yifan Zhu, Christopher Dunham
article en
6 citations

Abstract

While not all methods that estimate R<sub>t</sub> from wastewater produce the same results, they all provide a way to incorporate wastewater concentration data into epidemic modeling. Our results show that straightforward measures like the percent change can produce similar results of more complex models. Based on the results, researchers and public health officials can select the method that is best for their situation.

EpidemicsVol. 52
CDC Foundation (US), Stony Brook University (US), Syracuse University (US)
National Science Foundation, Syracuse University, Centers for Disease Control and Prevention
Clean water and sanitation
Openalex Percentile: Top 2%
SARS-CoV-2 detection and testing
8.38
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