Integrated miRNAome, transcriptome, and degradome analyses reveal the role of miRNA–mRNA modules in the biosynthesis of oridonin in Isodon rubescens

This study revealed that Ath-miR858b_1ss21GA could repress MYB transcription, potentially downregulating the specific genes involved in the biosynthesis of oridonin and reducing oridonin accumulation in <i>I. rubescens</i>.

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Publication Details

Journal
Frontiers in Plant Science
Published
2025-06-18
DOI
https://doi.org/10.3389/fpls.2025.1566354
Primary Topic
Bioactive Natural Diterpenoids Research
Type
article
Field-Weighted Citation Impact
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article

Integrated miRNAome, transcriptome, and degradome analyses reveal the role of miRNA–mRNA modules in the biosynthesis of oridonin in Isodon rubescens

Liping Dai, Zhimin Wang, Xiaoxiao Zhang, Hui Guo et al.
Frontiers in Plant Science
Bioactive Natural Diterpenoids Research
article

Integrated miRNAome, transcriptome, and degradome analyses reveal the role of miRNA–mRNA modules in the biosynthesis of oridonin in Isodon rubescens

Liping Dai, Zhimin Wang, Xiaoxiao Zhang, Hui Guo, Zihan Xu, Lili Zhu
article en

Abstract

This study revealed that Ath-miR858b_1ss21GA could repress MYB transcription, potentially downregulating the specific genes involved in the biosynthesis of oridonin and reducing oridonin accumulation in <i>I. rubescens</i>.

Frontiers in Plant ScienceVol. 16
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Henan University of Engineering (CN), China Academy of Chinese Medical Sciences (CN), First Affiliated Hospital of Henan University (CN)
Life in Land
Openalex Percentile: Top 87%
Bioactive Natural Diterpenoids Research
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