Epigenetic mechanisms linking atherosclerosis to ischemic stroke: insights from DNA methylation and transcriptome integration
This study highlights the pivotal role of epigenetic regulation in AS and IS, uncovering key pathways and molecular processes involved in their progression. Future studies should validate these findings in larger cohorts and integrate multi-omics approaches for a comprehensive understanding.
Authors
- Binrong Ding
- Zhengqing Wan (ORCID: https://orcid.org/0000-0002-9699-2811)
- Yiqun Wang (ORCID: https://orcid.org/0009-0006-2097-7312)
- Hao Wang (ORCID: https://orcid.org/0000-0001-9301-5989)
- Junfeng Li (ORCID: https://orcid.org/0000-0001-7672-5049)
- Xuewei Zhang (ORCID: https://orcid.org/0000-0003-4516-575X)
Institutions
- Central South University (CN)
- Hunan University (CN)
- Third Xiangya Hospital (CN)
- Xiangya Hospital Central South University (CN)
- Hunan Provincial Maternal and Child Health Hospital (CN)
- Changsha University of Science and Technology (CN)
- University of South China (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2025-06-18
- DOI
- https://doi.org/10.3389/fgene.2025.1567951
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Key Research and Development Program of China