Impact of CD11c+ cells in conducting airway lumen on Aspergillus fumigatus conidia deposition in neutropenic mice
Thus, detailed mapping of the conidial distribution patterns provides crucial insights into the spatial aspects of antifungal treatment in neutropenic patients. The enhanced contribution of CD11c<sup>+</sup> cells to conidial internalization in the conducting airway mucosa of neutropenic mice demonstrated in the present study emphasizes the potential of these cells in the development of more effective, cell-targeted antifungal treatments.
Authors
- Elena L. Bolkhovitina (ORCID: https://orcid.org/0000-0002-3386-509X)
- Valentin Borshchevskiy (ORCID: https://orcid.org/0000-0003-4398-9712)
- V. V. Shevchenko (ORCID: https://orcid.org/0000-0002-3164-3039)
- Mariia V. Pavelchenko (ORCID: https://orcid.org/0009-0006-2146-2396)
- Andrey Bogorodskiy (ORCID: https://orcid.org/0000-0002-7589-7823)
- Marina A. Shevchenko (ORCID: https://orcid.org/0000-0001-5278-9937)
- Alexander M. Sapozhnikov (ORCID: https://orcid.org/0000-0002-4934-677X)
- Svyatoslav Shalyapin
- Sergey Portnov
Institutions
- Moscow State Institute of Electronics and Mathematics (RU)
- National Research University Higher School of Economics (RU)
- Moscow Institute of Physics and Technology (RU)
- Joint Institute for Nuclear Research (RU)
- Institute of Bioorganic Chemistry (RU)
- National Research Nuclear University MEPhI (RU)
Publication Details
- Journal
- Frontiers in Fungal Biology
- Published
- 2025-06-18
- DOI
- https://doi.org/10.3389/ffunb.2025.1591891
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Russian Science Foundation