Integrative bioinformatics analysis and experimental validation reveals key genes and regulatory mechanisms in the development of gout
This study systematically elucidated the pivotal roles of CXCL8, PTGS2, and IL10 in gout pathogenesis, providing valuable molecular targets for therapeutic development.
Authors
- Jingguo Zhou
- Zhiqiang Gao (ORCID: https://orcid.org/0000-0001-9533-0288)
- Yi Liu (ORCID: https://orcid.org/0000-0002-3884-6605)
- Jianhong Chen (ORCID: https://orcid.org/0000-0003-2514-9840)
- Ye Yuan
Institutions
- First Affiliated Hospital of Chengdu Medical College (CN)
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2025-06-18
- DOI
- https://doi.org/10.3389/fgene.2025.1598835
- Citations
- 1
- Primary Topic
- Gout, Hyperuricemia, Uric Acid
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- Chengdu University of Traditional Chinese Medicine
- Chengdu University