Live bacteria found in gastric cancer tumor tissue
The live bacteria, including <i>L. salivarius</i>, <i>P. acnes</i>, and <i>K. pneumoniae</i>, have been found in gastric cancer tumor tissue. <i>P. acnes</i> specifically upregulate the oncogenic protein POF1B expression. The pathway through which this bacterium enters tumor tissue and its role in the tumor microenvironment require further investigation.
Authors
- Pengbo Guo (ORCID: https://orcid.org/0000-0002-2646-8133)
- Yinghui Zhao (ORCID: https://orcid.org/0000-0002-1933-8357)
- Hong Lin (ORCID: https://orcid.org/0000-0001-7336-9907)
- Xuewei Lv (ORCID: https://orcid.org/0000-0003-1690-4373)
- Rujian Zhang (ORCID: https://orcid.org/0009-0005-8013-0757)
- Haitao Wang (ORCID: https://orcid.org/0000-0003-4345-9375)
- Yu Wang (ORCID: https://orcid.org/0000-0001-6100-1312)
- Gang Lv (ORCID: https://orcid.org/0000-0002-1310-2087)
- Rui‐Hua Xu (ORCID: https://orcid.org/0000-0001-9771-8534)
- Pengxia Song
- Nianhua Zhang
Institutions
- Quzhou College of Technology (CN)
- Affiliated Hospital of Taishan Medical University (CN)
- Shandong Provincial QianFoShan Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-06-18
- DOI
- https://doi.org/10.3389/fmicb.2025.1591735
- Citations
- 2
- Primary Topic
- Cancer Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.47
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province
- Shandong First Medical University