Real-world efficacy and safety of cefepime for pediatric community-acquired pneumonia: a propensity score-matched study

Our results suggest that cefepime is a clinically effective and well-tolerated alternative to other broad-spectrum antibiotics for pediatric CAP, demonstrating comparable clinical outcomes and safety profiles. These findings support cefepime as a viable empiric therapy option, particularly in settings with limited microbiological diagnostics. Further studies are needed to confirm these results and optimize dosing strategies for pediatric populations.

Authors

Institutions

Publication Details

Journal
Frontiers in Cellular and Infection Microbiology
Published
2025-06-18
DOI
https://doi.org/10.3389/fcimb.2025.1616184
Citations
2
Primary Topic
Pneumonia and Respiratory Infections
Type
article
Field-Weighted Citation Impact
2.71

Funders

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article

Real-world efficacy and safety of cefepime for pediatric community-acquired pneumonia: a propensity score-matched study

Yanqing Song, Jingjing Deng, Changxin Liu, Yan Xing
2 citations
Frontiers in Cellular and Infection Microbiology
Pneumonia and Respiratory Infections
2.71
article

Real-world efficacy and safety of cefepime for pediatric community-acquired pneumonia: a propensity score-matched study

Yanqing Song, Jingjing Deng, Changxin Liu, Yan Xing
article en
2 citations

Abstract

Our results suggest that cefepime is a clinically effective and well-tolerated alternative to other broad-spectrum antibiotics for pediatric CAP, demonstrating comparable clinical outcomes and safety profiles. These findings support cefepime as a viable empiric therapy option, particularly in settings with limited microbiological diagnostics. Further studies are needed to confirm these results and optimize dosing strategies for pediatric populations.

Frontiers in Cellular and Infection MicrobiologyVol. 15
Jilin University (CN), First Hospital of Jilin University (CN), Changchun University (CN)
People's Government of Jilin Province, Health Commission of Jilin Province
Good health and well-being
Openalex Percentile: Top 10%
Pneumonia and Respiratory Infections
2.71
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Real-world efficacy and safety of cefepime for pediatric community-acquired pneumonia: a propensity score-matched study — Yanqing Song, Jingjing Deng, et al. · Frontiers in Cellular and Infection Microbiology (2025) | TGRS Research Map | TGRS