Rat retinal function attenuation with IOP elevation is impacted by both blood pressure and intracranial pressure
Retinal function is critically dependent on ocular perfusion pressure; excessive low or high perfusion attenuates function. The ocular perfusion pressure (BP-IOP) relationship largely accounts for the effect of IOP and BP modulation on retinal function but could not account for differences in ganglion cell function between ICP levels.
Authors
- Da Zhao (ORCID: https://orcid.org/0000-0002-9547-7017)
- Christine T. O. Nguyen (ORCID: https://orcid.org/0000-0002-3298-3086)
- Vickie Wong (ORCID: https://orcid.org/0000-0001-9356-7556)
- Bang V. Bui (ORCID: https://orcid.org/0000-0001-7298-1352)
- Zheng He (ORCID: https://orcid.org/0000-0001-6496-3971)
- Anna K. van Koeverden (ORCID: https://orcid.org/0000-0001-7435-7131)
- Sera N. Ganearachchi
Institutions
- The University of Melbourne (AU)
- Australian College of Optometry (AU)
Publication Details
- Journal
- Frontiers in Physiology
- Published
- 2025-06-18
- DOI
- https://doi.org/10.3389/fphys.2025.1566032
- Citations
- 1
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.71