Elevated monocyte-to-high-density lipoprotein ratio is associated with increased risk of cognitive impairment and severe cerebral small vessel disease burden
Elevated MHR is related to increased CSVD burden and CI. The mediating roles of severe CSVD burden indicates that a high MHR level may contribute to the progression of CSVD, thereby elevating the risk of CI.
Authors
- Peiyuan Lv
- Meixi Li
- Mengyao Zhao (ORCID: https://orcid.org/0000-0002-5038-8504)
- Yueshan Zhao (ORCID: https://orcid.org/0000-0001-6267-0171)
- Qishuo Yang (ORCID: https://orcid.org/0000-0003-0418-1227)
- Chao Wang (ORCID: https://orcid.org/0000-0001-6418-0504)
- Tianjun Wang (ORCID: https://orcid.org/0009-0009-9358-2137)
- J. Zhang (ORCID: https://orcid.org/0000-0001-8078-5394)
Institutions
- Hebei Medical University (CN)
- Hebei University of Economics and Business (CN)
- Hebei General Hospital (CN)
Publication Details
- Journal
- Frontiers in Aging Neuroscience
- Published
- 2025-06-18
- DOI
- https://doi.org/10.3389/fnagi.2025.1588488
- Citations
- 2
- Primary Topic
- Neurological Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.68