Landscape analysis of matrix metalloproteinases reveals key prognostic markers for prostate cancer
This study comprehensively explored the role of MMPs in PCa. Noteworthy, we further proved that MMP11 significantly promoted PCa probably through reprogramming of tumor microenvironment, which might provide a promising-target for PCa treatment.
Authors
- Jun Qiao (ORCID: https://orcid.org/0000-0001-7038-4538)
- Yuan Tian (ORCID: https://orcid.org/0000-0002-7717-2949)
- Ying Yu (ORCID: https://orcid.org/0000-0003-0925-0148)
- Yuewei Tao (ORCID: https://orcid.org/0000-0002-8059-8000)
- Wei Li (ORCID: https://orcid.org/0000-0001-9931-5990)
- Yanfeng Li (ORCID: https://orcid.org/0000-0002-8441-7721)
- Wei Xi
- Li Tao (ORCID: https://orcid.org/0000-0003-0851-1289)
- Qi Yu (ORCID: https://orcid.org/0000-0002-7240-6478)
Institutions
- Guiyang Medical University (CN)
- Ninewells Hospital (GB)
- Affiliated Hospital of Guizhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-06-18
- DOI
- https://doi.org/10.3389/fimmu.2025.1582992
- Citations
- 5
- Primary Topic
- Protease and Inhibitor Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 4.68
Funders
- Health Commission of Guizhou Province
- National Natural Science Foundation of China