High-flow nasal cannula versus non-invasive ventilation for acute exacerbations of chronic obstructive pulmonary disease with acute-moderate hypercapnic respiratory failure: a retrospective study
This study suggests similar overall treatment success rates for HFNC and NIV in AECOPD with AHRF. However, NIV appears more effective in achieving early respiratory improvements, whereas HFNC offers superior tolerability. Further large-scale, prospective, randomized controlled trials are warranted to definitively establish optimal respiratory support strategies for this patient population.
Authors
- Luigi Vetrugno (ORCID: https://orcid.org/0000-0003-3745-8368)
- Cristian Deana (ORCID: https://orcid.org/0000-0002-1626-3177)
- Mauro Castro-Sayat (ORCID: https://orcid.org/0000-0003-3490-553X)
- Ada Toledo (ORCID: https://orcid.org/0000-0001-6253-6239)
- Nicolás Colaianni-Alfonso (ORCID: https://orcid.org/0000-0002-1521-7363)
- Guillermo Montiel
Institutions
- University of Chieti-Pescara (IT)
- Hospital Fernández (AR)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-06-18
- DOI
- https://doi.org/10.3389/fmed.2025.1582749
- Citations
- 2
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 3.04