Brain white matter development in 8-year-old children is associated with maternal mental health during pregnancy
Our findings suggest that maternal depression and anxiety during pregnancy may have long-lasting impacts on offspring white matter microstructure maturation in the limbic system. This highlights the need for prenatal mental health screening and potential interventions to promote brain development and support optimal neurodevelopmental outcomes in children.
Authors
- Aline Andres (ORCID: https://orcid.org/0000-0003-2611-2193)
- Xiawei Ou (ORCID: https://orcid.org/0000-0001-9815-0127)
- Timothy R. Koscik (ORCID: https://orcid.org/0000-0002-2551-8127)
- Charles M. Glasier (ORCID: https://orcid.org/0000-0001-5202-1696)
- Yali Huang (ORCID: https://orcid.org/0000-0001-8263-6368)
- Jayne Bellando (ORCID: https://orcid.org/0000-0003-1986-6288)
- Adhitya Ram
Institutions
- Arkansas Children's Hospital (US)
- Arkansas Children's Nutrition Center (US)
- University of Arkansas at Fayetteville (US)
- University of Arkansas for Medical Sciences (US)
Publication Details
- Journal
- Frontiers in Human Neuroscience
- Published
- 2025-06-18
- DOI
- https://doi.org/10.3389/fnhum.2025.1603022
- Primary Topic
- Advanced Neuroimaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Agriculture