The association of CGG repeat length and AGG interruption patterns on FMR1 alleles with female infertility
Overall, the high normal sized (35-44 CGG) repeat length at both FMR1 alleles may serve a promoting role in the development of secondary infertility in Asian women. In addition, the CGG repeat length at allele 1 appears to have a mild correlation with AMH levels in infertile patients.
Authors
- Songchang Chen
- Shuyuan Li (ORCID: https://orcid.org/0000-0001-7428-3988)
- Naixin Xu
- Wei-hui Shi
- Xu Chen-ming
- Zhou Xuanyou
- Cao Xianling
Institutions
- Shanghai Jiao Tong University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- International Peace Maternity & Child Health Hospital (CN)
- Obstetrics and Gynecology Hospital of Fudan University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-06-17
- DOI
- https://doi.org/10.3389/fendo.2025.1609471
- Primary Topic
- Prenatal Screening and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China