Phleum pratense pollen-derived di-galactosyldiacylglycerols promote pro-allergic responses in mice
This study reveals for the first time the structure-dependent role of DGDG of TG pollen grains in immune cell recognition in the context of allergic inflammation. Our data may pave the way for therapies targeting lipid components in combination with protein allergens.
Authors
- Sylvia Düpow
- Katarzyna Duda (ORCID: https://orcid.org/0000-0001-5303-3760)
- Nestor González Roldán (ORCID: https://orcid.org/0000-0002-2799-9454)
- Yukari Fujimoto (ORCID: https://orcid.org/0000-0001-5320-3192)
- Dominik Schwudke (ORCID: https://orcid.org/0000-0002-1379-9451)
- Michael Wegmann (ORCID: https://orcid.org/0000-0002-1658-1554)
- Lars Lunding (ORCID: https://orcid.org/0000-0002-5278-3129)
Institutions
- Keio University (JP)
- German Center for Infection Research (DE)
- Research Center Borstel - Leibniz Lung Center (DE)
- German Center for Lung Research (DE)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-06-17
- DOI
- https://doi.org/10.3389/fimmu.2025.1532773
- Primary Topic
- Exercise and Physiological Responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsches Zentrum für Lungenforschung