A Spindle Cell Tumor in Disguise: Histoid Nodules Arising From Peripheral Nerves
A 25-year-old male presented with multiple, painless subcutaneous nodules, each measuring 5-6 mm, attached to thickened superficial cutaneous nerves. He also had nodular infiltration of the left earlobe. Histopathology revealed spindle-shaped histiocytes in a storiform pattern, with numerous acid-fast bacilli in Fite-Faraco staining. Skin slit smear from the nodule revealed a bacteriological index of +6. Ultrasonography of the nodule revealed a well-defined, avascular, heterogenous hypoechoic lesion over a focally thickened nerve with loss of fibrillary pattern, confirming a rare form of neural histoid leprosy.
Authors
- Josh Mathews (ORCID: https://orcid.org/0000-0002-5477-8470)
- Pratik Minj
- Ankur Patel (ORCID: https://orcid.org/0009-0004-0808-0321)
- A. Narula (ORCID: https://orcid.org/0009-0006-1638-6034)
Institutions
- All India Institute of Medical Sciences Bhopal (IN)
Publication Details
- Journal
- Cureus
- Published
- 2025-06-16
- DOI
- https://doi.org/10.7759/cureus.86173
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00