Unveiling the influence of caffeine on topiramate: metabolomic marker analysis using liquid chromatography-mass spectrometry

The findings highlight the potential of metabolomic approaches in uncovering novel biomarkers, which could enhance the management and development of therapeutic strategies for epilepsy. Moreover, we highlight the complex interactions between CAF and antiepileptic medications. Our findings establish a foundation for further research to understand lipid metabolism and its relevance in epilepsy, potentially guiding future therapeutic strategies.