Interleukin-1β mediates a tumor-supporting environment prompted by IGF1 in triple-negative breast cancer (TNBC)
IL-1β may be considered as a therapeutic target in more comprehensive approaches in obese TNBC patients exhibiting high IGF-1 bioavailability.
Authors
- Rosamaria Lappano (ORCID: https://orcid.org/0000-0002-9374-9701)
- F Silvestri (ORCID: https://orcid.org/0000-0003-2540-8267)
- Azzurra Zicarelli
- Francesca Cirillo (ORCID: https://orcid.org/0000-0003-2183-4226)
- Marianna Talia (ORCID: https://orcid.org/0000-0002-3440-5618)
- Salvatore De Rosis
- Domenica Scordamaglia (ORCID: https://orcid.org/0000-0001-8384-4230)
- Carlo Capalbo (ORCID: https://orcid.org/0000-0001-8445-6782)
- Anna Miglietta
- Marcello Maggiolini (ORCID: https://orcid.org/0000-0002-7485-854X)
- Antonino Belfiore (ORCID: https://orcid.org/0000-0002-8011-6382)
- Adelina Assunta Mondino
- Ernestina Marianna De Francesco
- Marika Di Dio
- Chiara Meliti
Institutions
- Università degli Studi di Enna Kore (IT)
- University of Catania (IT)
- Ospedale Garibaldi (IT)
- Ospedale Annunziata di Cosenza (IT)
- University of Calabria (IT)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-06-17
- DOI
- https://doi.org/10.1186/s12967-025-06730-w
- Citations
- 3
- Primary Topic
- Chemokine receptors and signaling
- Type
- article
- Field-Weighted Citation Impact
- 3.14
Funders
- Ministero dell'Università e della Ricerca