The diagnostic and prognostic role of novel biomarkers in anti-neutrophil cytoplasmic antibody-associated vasculitis
NLR, PLR, MLR, SII, and SIRI effectively distinguish AAV patients from controls and reflect disease activity, extent, and prognosis. While not standalone diagnostic tools, these markers offer valuable support to standard AAV assessment, particularly in challenging cases. Their accessibility suggests potential for enhancing clinical management, pending validation in larger cohorts.
Authors
- Shaoxiang Wang (ORCID: https://orcid.org/0000-0001-7653-4883)
- Yadan Zou
- Ting Long (ORCID: https://orcid.org/0000-0002-0136-8953)
- Ji Li (ORCID: https://orcid.org/0000-0003-0931-5562)
- Jing Zhang (ORCID: https://orcid.org/0000-0002-8449-6554)
- Shengguang Li (ORCID: https://orcid.org/0000-0003-4623-8607)
- Ruohan Yu
- Lína Zhang (ORCID: https://orcid.org/0000-0003-3671-8690)
Institutions
- Peking University (CN)
- Peking University International Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-06-17
- DOI
- https://doi.org/10.3389/fimmu.2025.1588287
- Citations
- 4
- Primary Topic
- Vasculitis and related conditions
- Type
- article
- Field-Weighted Citation Impact
- 6.07