Predictive value of the systemic inflammation grade for overall survival in patients with colorectal cancer after surgery: outperforming NLR and mGPS
SIG outperforms existing biomarkers and complements TNM staging by capturing systemic inflammation-driven risk heterogeneity. Its prognostic consistency across colon and rectal cancers supports its utility as a universal tool for postoperative risk stratification, guiding personalized adjuvant therapy and surveillance strategies.
Authors
- Jianing Wang (ORCID: https://orcid.org/0000-0001-5752-9050)
- Cuixia Liu (ORCID: https://orcid.org/0000-0003-3865-3499)
- Chao Cheng
- Wenliang Jiang (ORCID: https://orcid.org/0000-0002-2006-4605)
- Dongli Zhang (ORCID: https://orcid.org/0000-0002-0556-5532)
- Zhibin Zhao (ORCID: https://orcid.org/0000-0002-7245-3469)
- Yujun Liu
- Honggang Wang (ORCID: https://orcid.org/0000-0003-4761-0407)
Institutions
- Nantong University (CN)
- The Affiliated Taizhou People's Hospital of Nanjing Medical University (CN)
- Heilongjiang Provincial Hospital (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-06-17
- DOI
- https://doi.org/10.3389/fonc.2025.1529670
- Citations
- 2
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 2.09
Funders
- Nanjing Medical University