Identification of two KPC variants, KPC-204 and KPC-227, in ST11-K64 Klebsiella pneumoniae during prolonged hospitalization of a single patient
These findings highlight the high evolutionary potential of KPC enzymes and the importance of vigilance to curb the emergence and dissemination of resistance, which threatens the efficacy of critical lastresort antibiotics.
Authors
- Shijun Sun (ORCID: https://orcid.org/0000-0002-4389-541X)
- Wanhai Wang (ORCID: https://orcid.org/0000-0001-5354-5627)
- Chaoe Zhou
- Xinmin Liu (ORCID: https://orcid.org/0000-0002-3264-5255)
- S. Qi (ORCID: https://orcid.org/0009-0000-7983-0020)
- Liying Sun (ORCID: https://orcid.org/0000-0002-8744-4434)
- Haijun Li (ORCID: https://orcid.org/0000-0001-7165-1423)
Institutions
- Peking University (CN)
- Peking University First Hospital (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-06-17
- DOI
- https://doi.org/10.3389/fmicb.2025.1543470
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Zhengzhou University