Liposomes: A Versatile Drug Delivery System
Liposomes are microscopic vesicles composed of lipid bilayers that have emerged as a Versatile drug delivery system.Since their discovery in 1961 by Alec Douglas Bangham, liposomes have undergone significant advancements, offering a versatile platform for encapsulating hydrophilic, hydrophobic, and amphiphilic substances.This review highlights the classification, properties, mechanism of action, and preparation methods of liposomes.Various types of liposomes, including conventional, pH-sensitive, cationic, immune, and long-circulating liposomes, have been developed to cater to specific therapeutic needs.Liposomes have demonstrated enhanced therapeutic performance in treating cancer, fungal infections, and other diseases.The surface modification of this review highlights the classification, properties, mechanism, preparation methods, and clinical applications of liposomes, emphasizing their versatility and potential as a drug delivery system.
Authors
- Gajanan K. Rathod
- Pooja R. Hatwar (ORCID: https://orcid.org/0000-0002-5424-3425)
- Rupali A. Mendake
- Shriyog V. Amalkar
- Ravindra L. Bakal
Publication Details
- Journal
- International Journal of Pharmaceutical Sciences Review and Research
- Published
- 2025-05-01
- DOI
- https://doi.org/10.47583/ijpsrr.2025.v85i5.022
- Citations
- 2
- Primary Topic
- Nanoparticle-Based Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 1.19