Multi-omics analyses reveal altered gut microbial thiamine production in obesity
Our study highlights the impairment of microbial thiamine production and its broad associations with gut microbiota dysbiosis and obesity-related phenotypes. Our findings provide a rationale for developing treatments that utilize thiamine to prevent obesity by modulating gut microbiota.
Authors
- Xingyin Liu (ORCID: https://orcid.org/0000-0001-8770-3494)
- Weihong Ge (ORCID: https://orcid.org/0000-0001-5160-7855)
- Lulu Wang (ORCID: https://orcid.org/0000-0001-8079-4469)
- Yu Xia (ORCID: https://orcid.org/0000-0001-7647-4921)
- Yanyan Qiu
- Longya Lu
Institutions
- China Pharmaceutical University (CN)
- Southern University of Science and Technology (CN)
- Nanjing Drum Tower Hospital (CN)
- Guangxi University of Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-06-17
- DOI
- https://doi.org/10.3389/fmicb.2025.1516393
- Citations
- 6
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 6.99