Role of AI (Artificial Intelligence) Driven Synthesis of Antimicrobial Peptide (AMP) as a Potential Antibacterial Agent Against Multi-Drug Resistance (MDR) Pathogens-A Narrative Review
Antimicrobial peptide (AMP) is a small type of protein that has many antibacterial effects.In recent days antibiotic resistance is a serious problem Antibiotics alone cannot kill bacteria so combinatorial therapy shows some hope for eradicating bacterial resistance.The natural AMP shows less activity against bacteria rather synthetic AMP.In the meantime, scientists observed that AI-based AMPs are more effective than others.Various tools were introduced to synthesize AMP of our own choice like we can choose which AMP targets which sites This review specifically focuses on how different tools can synthesize various types of AMP, how they can be advantageous, some examples of AI-driven AMP that are in clinical trials and lastly how they can be a great hope for eradication of bacterial resistance.
Authors
- Sumantra Chatterjee (ORCID: https://orcid.org/0000-0002-5076-1698)
- Amalesh Samanta (ORCID: https://orcid.org/0000-0002-8502-7151)
- Shrestha Das (ORCID: https://orcid.org/0000-0002-2530-1438)
- Tamalika Chakraborty (ORCID: https://orcid.org/0000-0003-0646-196X)
- Shreya M. Banerjee (ORCID: https://orcid.org/0000-0003-1210-2162)
Publication Details
- Journal
- International Journal of Pharmaceutical Sciences Review and Research
- Published
- 2025-05-01
- DOI
- https://doi.org/10.47583/ijpsrr.2025.v85i5.025
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00