Role of AI (Artificial Intelligence) Driven Synthesis of Antimicrobial Peptide (AMP) as a Potential Antibacterial Agent Against Multi-Drug Resistance (MDR) Pathogens-A Narrative Review

Antimicrobial peptide (AMP) is a small type of protein that has many antibacterial effects.In recent days antibiotic resistance is a serious problem Antibiotics alone cannot kill bacteria so combinatorial therapy shows some hope for eradicating bacterial resistance.The natural AMP shows less activity against bacteria rather synthetic AMP.In the meantime, scientists observed that AI-based AMPs are more effective than others.Various tools were introduced to synthesize AMP of our own choice like we can choose which AMP targets which sites This review specifically focuses on how different tools can synthesize various types of AMP, how they can be advantageous, some examples of AI-driven AMP that are in clinical trials and lastly how they can be a great hope for eradication of bacterial resistance.

Authors

Publication Details

Journal
International Journal of Pharmaceutical Sciences Review and Research
Published
2025-05-01
DOI
https://doi.org/10.47583/ijpsrr.2025.v85i5.025
Primary Topic
Computational Drug Discovery Methods
Type
article
Field-Weighted Citation Impact
0.00
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article

Role of AI (Artificial Intelligence) Driven Synthesis of Antimicrobial Peptide (AMP) as a Potential Antibacterial Agent Against Multi-Drug Resistance (MDR) Pathogens-A Narrative Review

Sumantra Chatterjee, Amalesh Samanta, Shrestha Das, Tamalika Chakraborty et al.
1 links
International Journal of Pharmaceutical Sciences Review and Research
Computational Drug Discovery Methods
article

Role of AI (Artificial Intelligence) Driven Synthesis of Antimicrobial Peptide (AMP) as a Potential Antibacterial Agent Against Multi-Drug Resistance (MDR) Pathogens-A Narrative Review

Sumantra Chatterjee, Amalesh Samanta, Shrestha Das, Tamalika Chakraborty, Shreya M. Banerjee
article en

Abstract

Antimicrobial peptide (AMP) is a small type of protein that has many antibacterial effects.In recent days antibiotic resistance is a serious problem Antibiotics alone cannot kill bacteria so combinatorial therapy shows some hope for eradicating bacterial resistance.The natural AMP shows less activity against bacteria rather synthetic AMP.In the meantime, scientists observed that AI-based AMPs are more effective than others.Various tools were introduced to synthesize AMP of our own choice like we can choose which AMP targets which sites This review specifically focuses on how different tools can synthesize various types of AMP, how they can be advantageous, some examples of AI-driven AMP that are in clinical trials and lastly how they can be a great hope for eradication of bacterial resistance.

International Journal of Pharmaceutical Sciences Review and ResearchVol. 85(5)
Openalex Percentile: Top 85%
Computational Drug Discovery Methods
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