Cytokines in saliva, serum, and temporomandibular joint synovial fluid in children with juvenile idiopathic arthritis: An explorative cross-sectional study
In this exploratory study, several proinflammatory cytokines were found in higher concentrations in saliva in JIA-TMJ compared to saliva from the controls. No differences were seen in serum between the groups. Some pro- and anti-inflammatory cytokines detected in JIA-TMJ synovial fluid were found in higher concentrations compared to TMJ synovial fluid from healthy adult reference data.
Authors
- Marite Rygg (ORCID: https://orcid.org/0000-0001-5190-151X)
- Mohammed Al‐Haroni (ORCID: https://orcid.org/0000-0002-7347-7016)
- Astrid Jullumstrø Feuerherm (ORCID: https://orcid.org/0000-0001-5559-2072)
- Lena Cetrelli (ORCID: https://orcid.org/0000-0001-9643-517X)
- Berit Flatø (ORCID: https://orcid.org/0000-0002-5207-9182)
- Paula Frid (ORCID: https://orcid.org/0000-0002-7492-3479)
- Berit Tømmerås
- Per Alstergren (ORCID: https://orcid.org/0000-0002-8539-7742)
- Ellen Nordal (ORCID: https://orcid.org/0000-0001-5041-3928)
- Josefine Halbig (ORCID: https://orcid.org/0000-0002-0352-2969)
- Nils Thomas Songstad (ORCID: https://orcid.org/0000-0003-0343-5598)
- Veronika Rypdal (ORCID: https://orcid.org/0000-0003-3476-305X)
- Karen Rosendahl (ORCID: https://orcid.org/0000-0002-0135-2169)
- Annika Rosén (ORCID: https://orcid.org/0000-0003-0546-9089)
- Johanna Rykke Berstad
Institutions
- Oslo University Hospital (NO)
- University Hospital of North Norway (NO)
- Malmö University (SE)
- University of Oslo (NO)
- Norwegian University of Science and Technology (NO)
- Haukeland University Hospital (NO)
- St Olav's University Hospital (NO)
- Skåne University Hospital (SE)
- University of Bergen (NO)
- Northern Norway Regional Health Authority (NO)
- UiT The Arctic University of Norway (NO)
Publication Details
- Journal
- Pediatric Rheumatology
- Published
- 2025-06-17
- DOI
- https://doi.org/10.1186/s12969-025-01118-y
- Citations
- 1
- Primary Topic
- Autoimmune and Inflammatory Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 1.77
Funders
- Universitetet i Tromsø