Role for Complement <scp>C5</scp> in Eosinophilic Inflammation of Severe Asthma
We demonstrate a direct role for complement C5 in exacerbating eosinophilic inflammation in severe asthma.
Authors
- Huahao Shen (ORCID: https://orcid.org/0000-0001-9546-9351)
- Cong Dong (ORCID: https://orcid.org/0000-0003-1163-7966)
- Kewu Huang (ORCID: https://orcid.org/0000-0001-5882-9178)
- Xiaoyang Wei
- Kian Fan Chung (ORCID: https://orcid.org/0000-0001-7101-1426)
- Zhenan Deng (ORCID: https://orcid.org/0000-0002-8603-728X)
- Guochao Shi (ORCID: https://orcid.org/0000-0003-1987-8334)
- Zhongmin Qiu (ORCID: https://orcid.org/0000-0002-6612-7413)
- Xuliang Cai
- Wei Jiang (ORCID: https://orcid.org/0000-0002-1374-053X)
- Changxing Ou (ORCID: https://orcid.org/0000-0002-9993-4617)
- Zuofu Peng
- Qiang Li (ORCID: https://orcid.org/0000-0001-9503-995X)
- Changzheng Wang (ORCID: https://orcid.org/0000-0002-8991-1315)
- Qingling Zhang (ORCID: https://orcid.org/0000-0001-7353-524X)
- Wei Gu (ORCID: https://orcid.org/0000-0002-2723-0872)
- Xiangyan Zhang (ORCID: https://orcid.org/0000-0003-4410-0778)
- Shaohua Lu
- Xiuhua Fu
- Meiling Jin (ORCID: https://orcid.org/0000-0002-8663-0702)
- Nanshan Zhong (ORCID: https://orcid.org/0009-0008-7677-2572)
Institutions
- Tongji University (CN)
- Beijing Chao-Yang Hospital, Capital Medical University (CN)
- Ruijin Hospital (CN)
- Sinovac Biotech (CN)
- Harefield Hospital (GB)
- Chinese PLA General Hospital (CN)
- Royal Brompton Hospital (GB)
- First Affiliated Hospital of Guangzhou Medical University (CN)
- Zhongshan Hospital (CN)
- Shanghai First People's Hospital (CN)
- Guizhou Provincial People's Hospital (CN)
- State Key Laboratory of Respiratory Disease (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
- AstraZeneca (Germany) (DE)
- Tongji Hospital (CN)
- Inner Mongolia Medical University (CN)
- Imperial College London (GB)
- Galway-Mayo Institute of Technology (IE)
- Nanjing Medical University (CN)
- Chongqing Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Allergy
- Published
- 2025-06-16
- DOI
- https://doi.org/10.1111/all.16616
- Citations
- 2
- Primary Topic
- Complement system in diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.59
Funders
- National Natural Science Foundation of China