Role for Complement <scp>C5</scp> in Eosinophilic Inflammation of Severe Asthma

We demonstrate a direct role for complement C5 in exacerbating eosinophilic inflammation in severe asthma.

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Publication Details

Journal
Allergy
Published
2025-06-16
DOI
https://doi.org/10.1111/all.16616
Citations
2
Primary Topic
Complement system in diseases
Type
article
Field-Weighted Citation Impact
1.59

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article

Role for Complement C5 in Eosinophilic Inflammation of Severe Asthma

Huahao Shen, Cong Dong, Kewu Huang, Xiaoyang Wei et al.
2 citations
Allergy
Complement system in diseases
1.59
article

Role for Complement C5 in Eosinophilic Inflammation of Severe Asthma

Huahao Shen, Cong Dong, Kewu Huang, Xiaoyang Wei, Kian Fan Chung, Zhenan Deng, Guochao Shi, Zhongmin Qiu, Xuliang Cai, Wei Jiang, Changxing Ou, Zuofu Peng, Qiang Li, Changzheng Wang, Qingling Zhang, Wei Gu, Xiangyan Zhang, Shaohua Lu, Xiuhua Fu, Meiling Jin, Nanshan Zhong
article en
2 citations

Abstract

We demonstrate a direct role for complement C5 in exacerbating eosinophilic inflammation in severe asthma.

Allergy
Tongji University (CN), Beijing Chao-Yang Hospital, Capital Medical University (CN), Ruijin Hospital (CN), Sinovac Biotech (CN), Harefield Hospital (GB), Chinese PLA General Hospital (CN), Royal Brompton Hospital (GB), First Affiliated Hospital of Guangzhou Medical University (CN), Zhongshan Hospital (CN), Shanghai First People's Hospital (CN), Guizhou Provincial People's Hospital (CN), State Key Laboratory of Respiratory Disease (CN), Second Affiliated Hospital of Zhejiang University (CN), AstraZeneca (Germany) (DE), Tongji Hospital (CN), Inner Mongolia Medical University (CN), Imperial College London (GB), Galway-Mayo Institute of Technology (IE), Nanjing Medical University (CN), Chongqing Medical University (CN), Guangzhou Medical University (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 16%
Complement system in diseases
1.59
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