Immune Cell Phenotypes, Inflammatory Proteins and Epilepsy: A Mendelian Randomization Study to Investigate Causal Pathways

Emerging evidence implicates immune dysregulation and neuroinflammation in the pathogenesis of epilepsy, yet the causal mechanisms remain unclear. This study aimed to investigate the causal effects of immune cells and inflammatory proteins on epilepsy and evaluate the mediating role of inflammatory proteins.

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Publication Details

Journal
Neurosurgical Subspecialties
Published
2025-06-17
DOI
https://doi.org/10.14218/nsss.2025.00010
Primary Topic
Bioinformatics and Genomic Networks
Type
article
Field-Weighted Citation Impact
0.00

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article

Immune Cell Phenotypes, Inflammatory Proteins and Epilepsy: A Mendelian Randomization Study to Investigate Causal Pathways

M.-M. Liu, Jiancong Weng, Hong Tian, Hongdong Wang et al.
1 links
Neurosurgical Subspecialties
Bioinformatics and Genomic Networks
article

Immune Cell Phenotypes, Inflammatory Proteins and Epilepsy: A Mendelian Randomization Study to Investigate Causal Pathways

M.-M. Liu, Jiancong Weng, Hong Tian, Hongdong Wang, Xu Shao, Guizhi Wu
article en

Abstract

Emerging evidence implicates immune dysregulation and neuroinflammation in the pathogenesis of epilepsy, yet the causal mechanisms remain unclear. This study aimed to investigate the causal effects of immune cells and inflammatory proteins on epilepsy and evaluate the mediating role of inflammatory proteins.

Neurosurgical SubspecialtiesVol. 000(000)
National Natural Science Foundation of China, China-Japan Friendship Hospital
Openalex Percentile: Top 87%
Bioinformatics and Genomic Networks
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