Glomerular Haematopoietic Prostaglandin D Synthase‐Prostaglandin <scp>D2</scp> Axis Contributes to the Periodontitis‐Related Exacerbation of Diabetic Nephropathy in <scp>KK</scp>‐A<sup>y</sup> Mice
Periodontitis may contribute to DN progression via the glomerular HPGDS-PGD2 axis. These results suggest a novel mechanism in periodontitis-related DN progression.
Authors
- Tatsuro Zeze
- Takao Fukuda (ORCID: https://orcid.org/0000-0003-0430-1874)
- Yuki Nishimura (ORCID: https://orcid.org/0000-0002-4172-0472)
- Takanori Shinjo (ORCID: https://orcid.org/0000-0002-8269-2826)
- Terukazu Sanui (ORCID: https://orcid.org/0000-0002-5249-9574)
- Misaki Iwashita (ORCID: https://orcid.org/0000-0002-8557-346X)
- Naoichi Sato (ORCID: https://orcid.org/0000-0001-8674-8244)
- Hisashi Yokomizo (ORCID: https://orcid.org/0000-0001-7759-2014)
- Akiko Yamashita (ORCID: https://orcid.org/0000-0001-8845-8048)
- Kohei Sato
- Fusanori Nishimura (ORCID: https://orcid.org/0000-0003-1572-2180)
- Al‐kafee Ahmed
- Mio Imagawa
- Naoaki Ryo
- H. Otsuka
Institutions
- Kyushu University (JP)
- Kyushu Dental University (JP)
- Fukuoka University (JP)
- Nagasaki University (JP)
Publication Details
- Journal
- Journal Of Clinical Periodontology
- Published
- 2025-06-17
- DOI
- https://doi.org/10.1111/jcpe.14180
- Citations
- 2
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 2.93
Funders
- Suzuken Memorial Foundation
- Ministry of Education, Culture, Sports, Science and Technology
- Ichiro Kanehara Foundation for the Promotion of Medical Sciences and Medical Care
- 8020 Promotion Foundation
- Japan Society for the Promotion of Science
- Japan Science and Technology Agency