Anti‐melanogenic effects of <i>Medicago sativa</i> seed extracts on melanocytes
Alfalfa seed extracts exert an inhibitory effect on the melanin production process by modulating the activity of ERK, CREB and β-catenin, thereby suppressing MITF and reducing the levels of tyrosinase, TRP1 and DCT. Collectively, these findings suggest that alfalfa extracts may be a promising avenue for further research and development in the fields of cosmetics and pharmaceuticals.
Authors
- Chang‐Seok Lee
- Hee Jung Shin (ORCID: https://orcid.org/0000-0002-3398-1074)
- Kyeongmin Kim
- Chae Rin Kim
- Kyung‐Min Lim (ORCID: https://orcid.org/0000-0002-1517-7680)
- Min‐Ah Choi
- Junoh Kim (ORCID: https://orcid.org/0000-0003-0229-1430)
- Jung Woo (ORCID: https://orcid.org/0009-0000-6335-6387)
Institutions
- Ewha Womans University (KR)
- Eulji University (KR)
- Shinsung University (KR)
Publication Details
- Journal
- International Journal of Cosmetic Science
- Published
- 2025-06-17
- DOI
- https://doi.org/10.1111/ics.13092
- Primary Topic
- melanin and skin pigmentation
- Type
- article
- Field-Weighted Citation Impact
- 0.00