The Single Nucleotide Substitution T → A rs2072580 Damages the CREB1 Binding Site in the Bidirectional SART3/ISCU Promoter
The performed comprehensive functional analysis of the T → A rs2072580 in the bidirectional <i>SART3</i>/<i>ISCU</i> promoter unambiguously implies it is an rSNP. These results form the background for further studies of this rSNP and its potential significance for various pathologies.
Authors
- Arina Degtyareva
- Кonstantin E. Orishchenko (ORCID: https://orcid.org/0000-0001-9718-9038)
- E. V. Antontseva
- Т. И. Меркулова (ORCID: https://orcid.org/0000-0002-2707-0127)
- Anastasia Evseenko
Institutions
- Institute of Cytology and Genetics (RU)
Publication Details
- Journal
- Genes
- Published
- 2025-06-17
- DOI
- https://doi.org/10.3390/genes16060713
- Citations
- 2
- Primary Topic
- Endoplasmic Reticulum Stress and Disease
- Type
- article
- Field-Weighted Citation Impact
- 2.30