Development of niacinamide cosmetic bioadhesive emulgel using QbD approach
NMD was successfully vehiculized in a bioadhesive emulgel developed using the QbD approach. No significant changes in the critical quality attributes of the bioadhesive vehicle were observed after the incorporation of the active ingredient. The product, designed to present an increased residence time on the application site, provides a time frame to facilitate its performance, enabling the active ingredient to remain accumulated between the skin surface and its upper layers. Finally, and most importantly, QbD, a time-and cost-saving development approach that leads to high-quality products, proved to be an invaluable tool in this scientifically driven cosmetic project.
Authors
- María Celeste Palena (ORCID: https://orcid.org/0009-0008-9875-2214)
- Ana Teresa Ochoa-Andrade
- Rossannie Guasamucare (ORCID: https://orcid.org/0009-0001-7085-1949)
- Chiara Giorgi (ORCID: https://orcid.org/0009-0000-4210-9141)
- Yanina de Lafuente
- Emma Parente (ORCID: https://orcid.org/0000-0002-0279-6001)
- Alvaro F. Jimenez‐Kairuz (ORCID: https://orcid.org/0000-0003-1659-7983)
- María Sol Magi (ORCID: https://orcid.org/0009-0007-8482-4144)
Institutions
- Consejo Nacional de Investigaciones Científicas y Técnicas (AR)
- Universidad Nacional de Córdoba (AR)
- Universidad de la República de Uruguay (UY)
Publication Details
- Journal
- International Journal of Cosmetic Science
- Published
- 2025-06-17
- DOI
- https://doi.org/10.1111/ics.13083
- Citations
- 1
- Primary Topic
- Advancements in Transdermal Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.79
Funders
- Consejo Nacional de Investigaciones Científicas y Técnicas
- Universidad de la República Uruguay
- Secretaria de Ciencia y Tecnología - Universidad Nacional de Córdoba
- Agencia Nacional de Promoción Científica y Tecnológica
- Fondo para la Investigación Científica y Tecnológica