Concurrent Diagnosis of Superficial Esophageal Cancer and Esophageal Achalasia: A Case Report and Literature Review

We report a case of a 70-year-old woman with esophageal achalasia and concurrent superficial esophageal squamous cell carcinoma. Three adjacent superficial lesions were resected en bloc by endoscopic submucosal dissection (ESD), with no lymphovascular invasion. Given that the patient's dysphagia was effectively controlled with medication and dietary modifications, peroral endoscopic myotomy (POEM) was deferred following a careful assessment of the risk-benefit balance. As both ESD and POEM involve submucosal intervention, this case highlights the importance of individualized treatment based on symptom severity and lesion characteristics.

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Journal
DEN Open
Published
2025-06-17
DOI
https://doi.org/10.1002/deo2.70164
Primary Topic
Gastroesophageal reflux and treatments
Type
article
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0.00
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article

Concurrent Diagnosis of Superficial Esophageal Cancer and Esophageal Achalasia: A Case Report and Literature Review

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DEN Open
Gastroesophageal reflux and treatments
article

Concurrent Diagnosis of Superficial Esophageal Cancer and Esophageal Achalasia: A Case Report and Literature Review

Teppei Akimoto, Motohiko Kato, Takanori Kanai∥, Hideomi Tomida, Yusaku Takatori, Hideki Mori, Noriko Matsuura, Tatsuhiro Masaoka, Ai Katsumi, Hiroko Ando
article en

Abstract

We report a case of a 70-year-old woman with esophageal achalasia and concurrent superficial esophageal squamous cell carcinoma. Three adjacent superficial lesions were resected en bloc by endoscopic submucosal dissection (ESD), with no lymphovascular invasion. Given that the patient's dysphagia was effectively controlled with medication and dietary modifications, peroral endoscopic myotomy (POEM) was deferred following a careful assessment of the risk-benefit balance. As both ESD and POEM involve submucosal intervention, this case highlights the importance of individualized treatment based on symptom severity and lesion characteristics.

DEN OpenVol. 6(1)
Keio University (JP), Kawasaki Municipal Hospital (JP)
Good health and well-being
Openalex Percentile: Top 79%
Gastroesophageal reflux and treatments
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