CRISPR-Cas9-based electrochemical biosensor for the detection of <i>katG</i> gene mutations in isoniazid-resistant tuberculosis
The CRISPR/Cas9-based electrochemical biosensor exhibits high sensitivity and specificity for the detection <i>katG</i> mutation, offering a promising platform for rapid MDR-TB diagnostics.
Authors
- Mehmet Özsöz (ORCID: https://orcid.org/0000-0003-4037-3445)
- Safri Ishmayana (ORCID: https://orcid.org/0000-0002-9825-4425)
- Yeni Wahyuni Hartati (ORCID: https://orcid.org/0000-0003-1463-6352)
- Muhammad Ihda H.L. Zein (ORCID: https://orcid.org/0000-0001-6656-7315)
- Salma Nur Zakiyyah (ORCID: https://orcid.org/0000-0003-0985-5980)
- Irkham Irkham
- Dika Apriliana Wulandari
Institutions
- Mersin Üniversitesi (TR)
- Near East University (CY)
- Padjadjaran University (ID)
- University of Bologna (IT)
Publication Details
- Journal
- ADMET & DMPK
- Published
- 2025-06-17
- DOI
- https://doi.org/10.5599/admet.2766
- Citations
- 4
- Primary Topic
- CRISPR and Genetic Engineering
- Type
- article
- Field-Weighted Citation Impact
- 3.22
Funders
- Universitas Padjadjaran
- Kementerian Pendidikan, Kebudayaan, Riset, dan Teknologi