Laparoscopic Partial Splenectomy as a Spleen-Preserving Diagnostic Tool in a Case of Isolated Splenic Nodules

Solitary FDG-avid splenic lesions pose a diagnostic challenge due to the rarity of primary splenic tumors and the limitations of conventional biopsy techniques in this vascular organ. We present the case of a patient with a history of colorectal carcinoma who presented with isolated splenic nodules in whom a laparoscopic partial splenectomy was performed to obtain tissue for diagnosis. Histopathological analysis showed a low-grade follicular B-cell non-Hodgkin lymphoma, which led to the need for a completion splenectomy. This case underscores the diagnostic value of laparoscopic partial splenectomy in selected patients and highlights its role as a spleen-preserving alternative to total splenectomy.