A Restrictive Versus a Liberal Transfusion Strategy in Patients With Spontaneous Intracerebral Hemorrhage: A Secondary Analysis of TRAIN Randomized Clinical Trial

A liberal transfusion strategy was associated with a lower risk of mortality and organ failure, but not of unfavorable outcome in patients presenting with spontaneous ICH, compared with a restrictive strategy. However, the study cohort might have been underpowered to detect clinically relevant differences between the 2 interventions.

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Journal
Stroke
Published
2025-06-17
DOI
https://doi.org/10.1161/strokeaha.125.050729
Citations
1
Primary Topic
Intracerebral and Subarachnoid Hemorrhage Research
Type
article
Field-Weighted Citation Impact
1.39
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article

A Restrictive Versus a Liberal Transfusion Strategy in Patients With Spontaneous Intracerebral Hemorrhage: A Secondary Analysis of TRAIN Randomized Clinical Trial

Hervé Quintard, Pierre Bouzat, Jacques Duranteau, Evy Voets et al.
1 citations
Stroke
Intracerebral and Subarachnoid Hemorrhage Research
1.39
article

A Restrictive Versus a Liberal Transfusion Strategy in Patients With Spontaneous Intracerebral Hemorrhage: A Secondary Analysis of TRAIN Randomized Clinical Trial

Hervé Quintard, Pierre Bouzat, Jacques Duranteau, Evy Voets, Carla Bittencourt Rynkowski, Jean‐Louis Vincent, Wojciech Dąbrowski, Teemu M. Luoto, Luc Janssen, Ahmad Bayrlee, Helene Ravnholt Jensen, A Mándi, Rafael Badenes, Étienne Escudier, Fabio Silvio Taccone, Lara Bielsa Berrocal, Karim Lakhal, Olivier Huet, Erik Roman‐Pognuz, Stepani Bendel, Leda Nobile, Jihad Mallat, Elisa Gouvêa Bogossian, Eija Junttila, Maite Misis, Hussam Elkambergy, Jacques Créteur, Jorge Mejía-Mantilla, Markus Harboe Olsen, D. Durand, David Bougon, Jamil Dibu, Ainhoa Serrano, Pilar Marcos-Neira, Jasperina Dubois, Cássia Righy, Piet Lormans, Thomas Gargadennec, Rune Damgaard Nielsen, Aaron Blandino Ortíz, Umberto Lucangelo, Marco Antônio, Rehan Haque, Simona Šteblaj, Leire Pedrosa, Pilar Justo, Thomas Mistral, Claudia Díaz, Samuel Gay, Camilla Gelormini, Mohamed Elbahnasawy, Ximena Benavente, Charlotte Fernandez-Canal, Anselmo Caricato, Kirsten Møller, Eleonora Stival, Е. М. Строителева, Albrice Levrat, Luigi Zattera, Fatma Alawadhi, Antonio Maria Dell’Anna, Nahla AlJaberi, Angelo Giacomucci, Catherine Vandewaeter, Liese Mebis, Zied Hajjej, Xavier Wittebole, Raphaël Cinotti, Simona Steblaj, Haamid Siddique, Patricia Ormskerk, Manuel Quintana‐Díaz, Marie Lebouc, Valery V. Likhvantsev, Alexander Tsarev, Roberta T. Tallarico, Ata Mahmoodpoor, Serena Silva, Filippo Annoni, О. А. Гребенчиков, Samer Shoshan, Letícia Petterson, Caroline Abbenhuijs, Nancy Itesa Matumikina, Bruno De Oliveira, Ángela Marulanda, Igor Yovenko, Russell Chabanne, Kirsten Colpaert, Michel Sirodot, Gwenaëlle Desanglois, Olivier Simonet, Elena Perez Solada, Sara Maccherani, Lien Decaesteker, Ruth Demeersseman, Melanie Glasbergen-van Beijeren, Laura Nedolast, Dnyaneshwar Munde, Miguel Ulloa Bersatti, Karim Asenhoune, Alix Courouau, Naima Makouche, Carole Ichai, Berta López, Pauline Cam, Stela Velasco Eichler, Regina Roig Pineda, Ida Møller Larsen, Sara Chaffee, Isabel Gonzalez Perez, Giuliano Izzo, Pierluigi Banco, Pedro Kurtz, Andrés Saravia, Malligere Prasanna, Marjorie Beumier, Maximilian D’Onofrio, Charlotte Castelain, Chiara Faso, Nidya Funes
article en
1 citations

Abstract

A liberal transfusion strategy was associated with a lower risk of mortality and organ failure, but not of unfavorable outcome in patients presenting with spontaneous ICH, compared with a restrictive strategy. However, the study cohort might have been underpowered to detect clinically relevant differences between the 2 interventions.

StrokeVol. 56(9)
Medical University of Lublin (PL), University of Copenhagen (DK), Universidade Federal do Rio Grande do Sul (BR), Université Libre de Bruxelles (BE), Universidade Federal de Ciências da Saúde de Porto Alegre (BR), University of Trieste (IT), Inserm (FR), Université de Bretagne Occidentale (FR), Tabriz University of Medical Sciences (IR), Universidad de Alcalá (ES), Université Paris-Saclay (FR), Centre Hospitalier Universitaire de Grenoble (FR), Hospital Universitario La Paz (ES), Emirates Foundation (AE), Ljubljana University Medical Centre (SI), Erasmus Hospital (BE), Copenhagen University Hospital (DK), Hospital Universitari i Politècnic La Fe (ES), Faculdade Redentor (BR), Azienda Ospedaliera di Perugia (IT), Dr. Lucio Meléndez Hospital Zonal General de Agudos (AR), University Hospital of Geneva (CH), Hospital Clínic de Barcelona (ES), Tampere University Hospital (FI), Centre Hospitalier Régional Universitaire de Brest (FR), Tampere University (FI), AZ Delta (BE), Hospital Zonal General De Agudos Descentralizado "Evita Pueblo" (AR), Grenoble Institute of Neurosciences (FR), Hospital Universitario de León (ES), Bicêtre Hospital (FR), Instituto Estadual do Cérebro Paulo Niemeyer (BR), Catholic University of America (US), Université Grenoble Alpes (FR)
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Openalex Percentile: Top 19%
Intracerebral and Subarachnoid Hemorrhage Research
1.39
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