Large Stokes shift by increasing intramolecular charge transfer for high signal-to-background ratio bioimaging
Novel bicyclic 2-pyridone probes with strong electron donors (from Br in cDHIP-N-Br to dimethoxytriphenylamine in cDHIP-N-MTPA) exhibit redshifted emission (535-759 nm) and large Stokes shifts (≤320 nm) due to ICT effects, enabling high-contrast bioimaging in cells, tumor spheroids, and mice, showcasing their potential for advanced fluorescence imaging.
Authors
- Hui Tang (ORCID: https://orcid.org/0000-0002-6774-507X)
- Zhouyu Wang (ORCID: https://orcid.org/0000-0002-0704-2532)
- Xiao‐Qi Yu (ORCID: https://orcid.org/0000-0003-1719-6137)
- Xiao‐Yun Ran (ORCID: https://orcid.org/0000-0002-3588-4307)
- Qian Zhou (ORCID: https://orcid.org/0000-0001-9304-6216)
- Yong‐Ling Ban (ORCID: https://orcid.org/0000-0002-0226-9738)
- Ning Ma (ORCID: https://orcid.org/0000-0002-1938-7191)
- Shiyu Wu (ORCID: https://orcid.org/0009-0004-0358-8839)
- Yahui Zhang (ORCID: https://orcid.org/0000-0003-1888-2243)
Institutions
- Xihua University (CN)
- Sichuan University (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc02608c
- Citations
- 4
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 2.70