Single-cell and bulk transcriptome analysis identifies B-cell subpopulations and associated cancer subtypes with distinct clinical and molecular characteristics
Our study delineates eight B cell subpopulations with distinct prognostic relevance. Signature-based stratification and models underscore their clinical relevance in cancer outcomes and therapy response, advancing understanding of B cell heterogeneity in cancer.
Authors
- Yufen Zheng (ORCID: https://orcid.org/0000-0002-5140-5521)
- Li Zhao (ORCID: https://orcid.org/0000-0003-1576-8787)
- Y. He (ORCID: https://orcid.org/0009-0009-8662-356X)
- Xiaosheng Wang
Institutions
- China Pharmaceutical University (CN)
Publication Details
- Journal
- Cellular Oncology
- Published
- 2025-06-17
- DOI
- https://doi.org/10.1007/s13402-025-01082-5
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- China Pharmaceutical University