Coexistence of Lichen Planus and Squamous Cell Carcinoma on Sun-Exposed Skin: A Case Report

Lichen planus (LP) is a chronic idiopathic skin disorder that has a predilection for sun-exposed areas. Although rare, there is a possibility that chronic LP lesions could progress to squamous cell carcinoma (SCC), a non-melanocytic malignant skin neoplasm. Cumulative exposure to ultraviolet radiation, particularly in individuals with lighter skin tones, is one of the leading risk factors for cutaneous SCC (cSCC). In this report, we present a case of a 79-year-old male patient who was diagnosed with a moderately differentiated cSCC with facial localization. This condition developed on the background of preexisting actinic keratosis, and was accompanied by a LP.

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Publication Details

Journal
Cureus
Published
2025-06-17
DOI
https://doi.org/10.7759/cureus.86194
Primary Topic
Nonmelanoma Skin Cancer Studies
Type
article
Field-Weighted Citation Impact
0.00
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Coexistence of Lichen Planus and Squamous Cell Carcinoma on Sun-Exposed Skin: A Case Report

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Coexistence of Lichen Planus and Squamous Cell Carcinoma on Sun-Exposed Skin: A Case Report

George S Stoyanov, Kristina Naydenova, Hristo Popov, Adelina V Velikova, Anastasia I Bekyarova, A. Kirilova
article en

Abstract

Lichen planus (LP) is a chronic idiopathic skin disorder that has a predilection for sun-exposed areas. Although rare, there is a possibility that chronic LP lesions could progress to squamous cell carcinoma (SCC), a non-melanocytic malignant skin neoplasm. Cumulative exposure to ultraviolet radiation, particularly in individuals with lighter skin tones, is one of the leading risk factors for cutaneous SCC (cSCC). In this report, we present a case of a 79-year-old male patient who was diagnosed with a moderately differentiated cSCC with facial localization. This condition developed on the background of preexisting actinic keratosis, and was accompanied by a LP.

CureusVol. 17(6)
Medical University of Varna (BG), National Institute of Emergency Medicine "Pirogov" (BG)
Openalex Percentile: Top 80%
Nonmelanoma Skin Cancer Studies
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