Neonatal <scp>CARD14</scp> ‐Associated Papulosquamous Eruption: Response to Secukinumab During Infancy

Neonatal erythroderma is a rare but serious condition characterized by generalized erythema and scaling present from birth or shortly after. We report a case of neonatal erythroderma in a 3-week-old male related to a heterozygous mutation in the CARD14 gene. The successful use of secukinumab adds an additional case to underscore the potential of targeted biologic therapies in treating severe neonatal inflammatory conditions.

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Publication Details

Journal
Pediatric Dermatology
Published
2025-06-17
DOI
https://doi.org/10.1111/pde.16003
Citations
1
Primary Topic
Skin and Cellular Biology Research
Type
article
Field-Weighted Citation Impact
1.15
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article

Neonatal CARD14 ‐Associated Papulosquamous Eruption: Response to Secukinumab During Infancy

Sílvia Planas, Cristian Launes, Eulàlia Baselga, Álvaro March‐Rodríguez et al.
1 citations
Pediatric Dermatology
Skin and Cellular Biology Research
1.15
article

Neonatal CARD14 ‐Associated Papulosquamous Eruption: Response to Secukinumab During Infancy

Sílvia Planas, Cristian Launes, Eulàlia Baselga, Álvaro March‐Rodríguez, Ramón M. Pujol, Helena Escolà, Lilia Sánchez, Luis A. Pérez‐Jurado, Ana García‐García, Asunción Vicente
article en
1 citations

Abstract

Neonatal erythroderma is a rare but serious condition characterized by generalized erythema and scaling present from birth or shortly after. We report a case of neonatal erythroderma in a 3-week-old male related to a heterozygous mutation in the CARD14 gene. The successful use of secukinumab adds an additional case to underscore the potential of targeted biologic therapies in treating severe neonatal inflammatory conditions.

Pediatric DermatologyVol. 42(6)
Hospital Sant Joan de Déu Barcelona (ES), Universitat Pompeu Fabra (ES), Centre for Biomedical Network Research on Rare Diseases (ES), Hospital Clínic de Barcelona (ES), Hospital Del Mar (ES), Universitat de Barcelona (ES)
Good health and well-being
Openalex Percentile: Top 23%
Skin and Cellular Biology Research
1.15
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Neonatal <scp>CARD14</scp> ‐Associated Papulosquamous Eruption: Response to Secukinumab During Infancy — Sílvia Planas, Cristian Launes, et al. · Pediatric Dermatology (2025) | TGRS Research Map | TGRS