Effectiveness and tolerability of liraglutide as add‐on treatment in patients with obesity and high‐frequency or chronic migraine: A prospective pilot study

Our findings show that liraglutide may be effective in the treatment of unresponsive high-frequency or chronic migraine in patients with obesity, and that this effect is independent from weight loss. Although further studies are needed to clarify this topic, these findings generate the hypothesis that a derangement in ICP control may play a role in migraine pathogenesis and potentially represent a novel therapeutic target.

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Publication Details

Journal
Headache The Journal of Head and Face Pain
Published
2025-06-17
DOI
https://doi.org/10.1111/head.14991
Citations
7
Primary Topic
Migraine and Headache Studies
Type
article
Field-Weighted Citation Impact
10.30
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article

Effectiveness and tolerability of liraglutide as add‐on treatment in patients with obesity and high‐frequency or chronic migraine: A prospective pilot study

Antonio Stornaiuolo, Gennaro Cretella, Roberto De Simone, Cinzia Valeria Russo et al.
7 citations
Headache The Journal of Head and Face Pain
Migraine and Headache Studies
10.30
article

Effectiveness and tolerability of liraglutide as add‐on treatment in patients with obesity and high‐frequency or chronic migraine: A prospective pilot study

Antonio Stornaiuolo, Gennaro Cretella, Roberto De Simone, Cinzia Valeria Russo, Simone Braca, Caterina Giannini, Angelo Miele
article en
7 citations

Abstract

Our findings show that liraglutide may be effective in the treatment of unresponsive high-frequency or chronic migraine in patients with obesity, and that this effect is independent from weight loss. Although further studies are needed to clarify this topic, these findings generate the hypothesis that a derangement in ICP control may play a role in migraine pathogenesis and potentially represent a novel therapeutic target.

Headache The Journal of Head and Face PainVol. 65(10)
University of Naples Federico II (IT)
Good health and well-being
Openalex Percentile: Top 1%
Migraine and Headache Studies
10.30
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